1-METHYLHISTAMINE DIHYDROCHLORIDE
Synonym(s):1-Methyl-4-(β-aminoethyl)imidazole dihydrochloride
- CAS NO.：6481-48-7
- Empirical Formula: C6H13Cl2N3
- Molecular Weight: 198.09
- MDL number: MFCD00037000
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is 1-METHYLHISTAMINE DIHYDROCHLORIDE?
Description
1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer’s disease patients as well as those with hypersomnia and other neurological conditions.
The Uses of 1-METHYLHISTAMINE DIHYDROCHLORIDE
1-Methylhistamine Dihydrochloride is a selective H1-receptor agonists. Also it has depressant effects.
Biochem/physiol Actions
Major metabolite of histamine by histamine N-methyltransferase.
Properties of 1-METHYLHISTAMINE DIHYDROCHLORIDE
| Melting point: | >198°C (dec.) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | powder |
| color | Pale Yellow |
| Stability: | Hygroscopic |
Safety information for 1-METHYLHISTAMINE DIHYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-METHYLHISTAMINE DIHYDROCHLORIDE
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
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