[1-METHYL-1-(PYRIDIN-2-YL)ETHYL]AMINE
Synonym(s):PIP;PIP Directing Group;Shi Auxilliary
- CAS NO.：52568-28-2
- Empirical Formula: C8H12N2
- Molecular Weight: 136.19
- MDL number: MFCD08729302
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 06:25:12
![[1-METHYL-1-(PYRIDIN-2-YL)ETHYL]AMINE Structural](https://img.chemicalbook.in/CAS/GIF/52568-28-2.gif)
What is [1-METHYL-1-(PYRIDIN-2-YL)ETHYL]AMINE?
The Uses of [1-METHYL-1-(PYRIDIN-2-YL)ETHYL]AMINE
The Shi Auxiliary is a powerful directing group for the hydroxylation of arenes through copper-mediated C-H activation. This useful auxiliary can be removed through acid-mediated hydrolysis and has shown to be done on gram-scale.
General Description
2-(Pyridin-2-yl)isopropyl amine (PIP-amine) is a tertiary amine. A bidentate directing group, useful for the functionalization of C-H bond, has been developed from PIP-amine.
Properties of [1-METHYL-1-(PYRIDIN-2-YL)ETHYL]AMINE
| Boiling point: | 212.7±15.0 °C(Predicted) |
| Density | 0.9800 g/mL at 25℃ |
| refractive index | n/D1.516 |
| Flash point: | 79℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | liquid |
| pka | 9.40±0.50(Predicted) |
Safety information for [1-METHYL-1-(PYRIDIN-2-YL)ETHYL]AMINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for [1-METHYL-1-(PYRIDIN-2-YL)ETHYL]AMINE
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
![2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-MORPHOLINO-2-[3-(TRIFLUOROMETHYL)PHENYL]ACETONITRILE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB7170089.gif)
![2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-MORPHOLINO-2-(2-THIENYL)ACETONITRILE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB9246838.gif)
![2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-MORPHOLINO-4-PHENYL-3-BUTENENITRILE](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB3776623.gif)
![2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-MORPHOLINO-2-(4-PYRIDINYL)ACETONITRILE](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB9781744.gif)
![2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-MORPHOLINO-2-(2-PYRIDINYL)ACETONITRILE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2386951.gif)
![2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-(2-FLUOROPHENYL)-2-MORPHOLINOACETONITRILE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB4719148.gif)
You may like
-
2-(Pyridin-2-yl)isopropyl amine CAS 52568-28-2View Details
52568-28-2 -
Product IntroductionView Details -
Product InrtroductionView Details -
DGO24View Details -
DGO25View Details -
DGO29View Details -
DGO32View Details -
DGO36View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.