1-(4-Pyridyl)piperazine
Synonym(s):4-Piperazinopyridine
- CAS NO.：1008-91-9
- Empirical Formula: C9H13N3
- Molecular Weight: 163.22
- MDL number: MFCD00040745
- EINECS: 213-764-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is 1-(4-Pyridyl)piperazine?
The Uses of 1-(4-Pyridyl)piperazine
1-(4-Pyridyl)piperazine is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals. It is also used to produce 1-pyridin-4-yl-4-(4-vinyl-benzyl)-piperazine with 1-(chloromethyl)-4-vinylbenzene by heating.
General Description
1-(4-Pyridyl) piperazine (or 4-Piperazinopyridine) is an active structural component that is used as a building block to prepare various medicinally important active molecules.
Properties of 1-(4-Pyridyl)piperazine
| Melting point: | 137-141 °C |
| Boiling point: | 195-200°C 0,3mm |
| Density | 1.081±0.06 g/cm3(Predicted) |
| Flash point: | 195-200°C/0.3mm |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 10.73±0.10(Predicted) |
| color | White to Light yellow |
| Water Solubility | Soluble in water. |
| Sensitive | Air Sensitive |
| BRN | 609705 |
| Stability: | Air Sensitive |
| CAS DataBase Reference | 1008-91-9(CAS DataBase Reference) |
Safety information for 1-(4-Pyridyl)piperazine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(4-Pyridyl)piperazine
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