1-(4-Pyridyl)piperazine

Synonym(s):4-Piperazinopyridine

CAS NO.：1008-91-9
Empirical Formula: C9H13N3
Molecular Weight: 163.22
MDL number: MFCD00040745
EINECS: 213-764-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-06-04 16:00:12

What is 1-(4-Pyridyl)piperazine?

The Uses of 1-(4-Pyridyl)piperazine

1-(4-Pyridyl)piperazine is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals. It is also used to produce 1-pyridin-4-yl-4-(4-vinyl-benzyl)-piperazine with 1-(chloromethyl)-4-vinylbenzene by heating.

General Description

1-(4-Pyridyl) piperazine (or 4-Piperazinopyridine) is an active structural component that is used as a building block to prepare various medicinally important active molecules.

Properties of 1-(4-Pyridyl)piperazine

Melting point:	137-141 °C
Boiling point:	195-200°C 0,3mm
Density	1.081±0.06 g/cm3(Predicted)
Flash point:	195-200°C/0.3mm
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	soluble in Methanol
form	powder to crystal
pka	10.73±0.10(Predicted)
color	White to Light yellow
Water Solubility	Soluble in water.
Sensitive	Air Sensitive
BRN	609705
Stability:	Air Sensitive
CAS DataBase Reference	1008-91-9(CAS DataBase Reference)

Safety information for 1-(4-Pyridyl)piperazine

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.