trans-1-Cinnamylpiperazine

CAS NO.：87179-40-6
Empirical Formula: C13H18N2
Molecular Weight: 202.3
MDL number: MFCD00063251
EINECS: 673-639-1
SAFETY DATA SHEET (SDS)
Update Date: 2025-07-14 15:28:00

What is trans-1-Cinnamylpiperazine?

Description

trans-1-Cinnamylpiperazine is a piperazine derivative. It was used as a test compound to investigate the in vitro efficacy as an antiprotozoal against Philasterides dicentrarchi. It may be used to synthesize Incentrom A derivatives.

Chemical properties

clear colorless to yellow liquid

The Uses of trans-1-Cinnamylpiperazine

trans-1-Cinnamylpiperazine is used in the synthesis of bile acid piperazinyl derivatives which display pro-apoptotic properties on carcinoma human cell lines.

The Uses of trans-1-Cinnamylpiperazine

trans-1-Cinnamylpiperazine was used as a test compound to investigate the in vitro efficacy as an antiprotozoal against Philasterides dicentrarchi. It may be used to synthesize Incentrom A derivatives.

General Description

trans-1-Cinnamylpiperazine is a piperazine derivative.

General Description

trans-1-Cinnamylpiperazine is an important organic synthetic reagent for the preparation of opioid tripeptides hybridised with trans-1-Cinnamylpiperazine, which exhibits low haematotoxicity and good cancer cell growth as an inhibitor of pancreatic cancer cell proliferation in two- and three-dimensional in vitro models Inhibition. It was also used in the preparation of the anticonvulsant active substance cinnamylpiperazine derivatives.

Properties of trans-1-Cinnamylpiperazine

Melting point:	39-44 °C(lit.)
Boiling point:	129 °C1 mm Hg(lit.)
Density	0.989 g/mL at 25 °C(lit.)
refractive index	1.574-1.576
Flash point:	>230 °F
storage temp.	Refrigerator, under inert atmosphere
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Solid
pka	9.17±0.10(Predicted)
color	Pale Yellow
BRN	608984
InChI	InChI=1S/C13H18N2/c1-2-5-13(6-3-1)7-4-10-15-11-8-14-9-12-15/h1-7,14H,8-12H2/b7-4+
CAS DataBase Reference	87179-40-6(CAS DataBase Reference)

Safety information for trans-1-Cinnamylpiperazine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.