1-[3-(9H-Carbazol-9-yl)propyl]-4-(2-methoxyphenyl)-4-piperidinol hydrochloride

CAS NO.：184845-43-0
Empirical Formula: C27H30N2O2
Molecular Weight: 414.54
MDL number: MFCD00952020
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:49:05

What is 1-[3-(9H-Carbazol-9-yl)propyl]-4-(2-methoxyphenyl)-4-piperidinol hydrochloride?

The Uses of 1-[3-(9H-Carbazol-9-yl)propyl]-4-(2-methoxyphenyl)-4-piperidinol hydrochloride

NNC 05-2090 Hydrochloride is a GABA uptake inhibitor displaying selectivity for BGT-1 (mGAT-2) transporters.

What are the applications of Application

NNC 05-2090 hydrochloride is a GABA uptake inhibitor displaying selectivity for BGT-1 (mGAT-2) transporters

Biological Activity

GABA uptake inhibitor that displays moderate selectivity for BGT-1 (mGAT-2) transporters (K i values are 1.4, 15, 19 and 41 μ M for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively). Anticonvulsive; inhibits sound-induced tonic and clonic convulsions in DBA/2 mice. Also displays affinity at α 1 - and D 2 -receptors (IC 50 values are 266 and 1632 nM respectively).

Properties of 1-[3-(9H-Carbazol-9-yl)propyl]-4-(2-methoxyphenyl)-4-piperidinol hydrochloride

Boiling point:	623.5±55.0 °C(Predicted)
Density	1.17±0.1 g/cm3(Predicted)
storage temp.	Desiccate at RT
pka	14.13±0.20(Predicted)

Safety information for 1-[3-(9H-Carbazol-9-yl)propyl]-4-(2-methoxyphenyl)-4-piperidinol hydrochloride

Computed Descriptors for 1-[3-(9H-Carbazol-9-yl)propyl]-4-(2-methoxyphenyl)-4-piperidinol hydrochloride

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Related products of tetrahydrofuran

1-(3-AMINO-PROPYL)-PIPERIDIN-4-OL

4-(2-METHOXY-PHENYL)-PIPERIDIN-4-OL

1-[3-(9H-CARBAZOL-9-YL)PROPYL]-4-(2-METHOXYPHENYL)-4-PIPERIDINOL HYDROCHLORIDE