1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)-beta-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine

CAS NO.：444717-23-1
Empirical Formula: C42H43N3O13S
Molecular Weight: 829.87
MDL number: MFCD08061410
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:50:13

What is 1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)-beta-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine?

Chemical properties

Yellowish amorphous solid

The Uses of 1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)-beta-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine

3-N-Boc-5'-O-DMT-3'-O-nosylthymidine (CAS# 444717-23-1) is a useful research chemical compound. It is used in the radio-synthesis of 18F-labeled deoxyfluorothymidine as radiopharmaceutical for PET by fluorination via nucleophilic substitution of precursor.

Properties of 1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)-beta-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine

Melting point:	105 - 122°C
Boiling point:	879.8±75.0 °C(Predicted)
Density	1.42±0.1 g/cm3(Predicted)
storage temp.	Refrigerator, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	-3.02±0.40(Predicted)
color	Light Yellow to Yellow
Stability:	Unstable in Aqueous Solution
CAS DataBase Reference	444717-23-1

Safety information for 1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)-beta-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine

Computed Descriptors for 1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)-beta-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine

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