1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
- CAS NO.：110283-66-4
- Empirical Formula: C23H22ClF6NO3
- Molecular Weight: 509.87
- MDL number: MFCD00889186
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
![1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE Structural](https://img.chemicalbook.in/CAS/GIF/110283-66-4.gif)
What is 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE?
The Uses of 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
CI-966 Hydrochloride is highly selective for the cloned GABA transporter GAT-1. CI 966 Hydrochloride is a GABA transport inhibitor.
What are the applications of Application
CI 966 hydrochloride is a selective inhibitor of GABA T-1
Biological Activity
Selective inhibitor of the GABA transporter GAT-1 (IC 50 values are 0.26 and 1.2 μ M at cloned human and rat GAT-1 respectively). Displays over 200-fold selectivity over GAT-2 and GAT-3. Centrally active upon systemic administration in vivo . Anticonvulsive and neuroprotective.
Storage
Desiccate at RT
Properties of 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
| Melting point: | 240-244 °C |
| storage temp. | Desiccate at RT |
| solubility | Soluble to 10 mM in ethanol and to 100 mM in DMSO |
| form | Solid |
| color | White to off-white |
Safety information for 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
Computed Descriptors for 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
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![(R)-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHANOL](https://img.chemicalbook.in/CAS/GIF/76155-79-8.gif)
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