(+)-MK 801 MALEATE

The Uses of (+)-MK 801 MALEATE

Biochemical probe for NMDA receptors.

What are the applications of Application

(?)-MK 801 maleate is an NMDA receptor antagonist

General Description

(-)-MK-801 hydrogen maleate is a less potent stereoisomer of (+)-MK-801.

Biological Activity

Less active enantiomer (10-fold less potent in behavioral studies) than (+)-MK 801 maleate ((5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate ).

Biochem/physiol Actions

Less active enantiomer of (+)-MK-801 hydrogen maleate