(-)-[3R,4S]-CHROMANOL 293B
- CAS NO.：163163-24-4
- Empirical Formula: C15H20N2O4S
- Molecular Weight: 324.4
- MDL number: MFCD06798368
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
![(-)-[3R,4S]-CHROMANOL 293B Structural](https://img.chemicalbook.in/CAS/GIF/163163-24-4.gif)
What is (-)-[3R,4S]-CHROMANOL 293B?
What are the applications of Application
(?)-[3R,4S]-Chromanol 293B is a selective inhibitor of the slow component of delayed rectifier K+ current
Definition
ChEBI: Chromanol 293B is a 1-benzopyran.
Biological Activity
Enantiomer that selectively inhibits the slow component of delayed rectifier K + current (I Ks ). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC 50 values are 1.36 and 9.6 μ M respectively). Has negligible inhibitory action at hERG channels (IC 50 > 30 μ M).
Storage
Room temperature
Properties of (-)-[3R,4S]-CHROMANOL 293B
| Melting point: | 192 °C |
| Boiling point: | 474.1±55.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO: 18 mg/mL |
| form | solid |
| pka | 12.96±0.60(Predicted) |
| color | white |
Safety information for (-)-[3R,4S]-CHROMANOL 293B
Computed Descriptors for (-)-[3R,4S]-CHROMANOL 293B
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