129-74-8
Product Name:
BUCLIZINE, DIHYDROCHLORIDE
Formula:
C28H35Cl3N2
Synonyms:
1-(p-Chloro-α-phenylbenzyl)-4-(p-tert-butylbenzyl)piperazine;1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)-diethylenediamine hydrochloride;1-[(4-Chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-piperazine dihydrochloride;Buclina;Longifene
Inquiry
COMPUTED DESCRIPTORS
| Molecular Weight | 505.9 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 6 |
| Exact Mass | 504.186582 g/mol |
| Monoisotopic Mass | 504.186582 g/mol |
| Topological Polar Surface Area | 6.5 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 514 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 3 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Buclizine dihydrochloride is a hydrochloride salt that is obtained by reaction of buclizine with 2 equivalents of hydrogen chloride. It has a role as a central nervous system depressant, a local anaesthetic, a histamine antagonist, a cholinergic antagonist and an antiemetic. It contains a buclizine(2+).