114870-03-0
Product Name:
Fondaparinux sodium
Formula:
C31H43N3O49S8.10Na
Synonyms:
Fondaparin sodium;Fondaparinux sodium;SR-90107A
Inquiry
COMPUTED DESCRIPTORS
| Molecular Weight | 1728.1 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 9 |
| Hydrogen Bond Acceptor Count | 52 |
| Rotatable Bond Count | 20 |
| Exact Mass | 1726.7707769 g/mol |
| Monoisotopic Mass | 1726.7707769 g/mol |
| Topological Polar Surface Area | 901 Ų |
| Heavy Atom Count | 101 |
| Formal Charge | 0 |
| Complexity | 3330 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 25 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 11 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Fondaparinux Sodium is the sodium salt form of fondaparinux, a synthetic glucopyranoside with antithrombotic activity. Fondaparinux sodium selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development. (NCI05)