Zanamivir-13C,15N2
- CAS NO.:1276528-62-1
- Empirical Formula: C12H20N4O7
- Molecular Weight: 332.3098
- MDL number: MFCD28899480
- Update Date: 2023-05-18 11:31:19
What is Zanamivir-13C,15N2?
Description
Zanamivir-13C,15N2 is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles. It has been shown to selectively inhibit the growth of influenza A and B viruses in plaque reduction assays with IC50 values ranging from 5 to 14 nM and to directly inhibit influenza A and B virus neuraminidases with IC50 values ranging from 0.6 to 7.9 nM in vitro. Intranasal zanamivir administration at 0.4 mg/kg twice daily reduces mortality and viral titers in lung homogenates of mice infected with influenza.
Chemical properties
White Solid
The Uses of Zanamivir-13C,15N2
Influenza viral neuraminidase inhibitor; structural analog of the sialic acid. Antiviral.
What are the applications of Application
Zanamivir-13C,15N2 is an influenza viral neuraminidase inhibitor
Properties of Zanamivir-13C,15N2
| Melting point: | >2400C (dec.) |
| storage temp. | -20°C Freezer |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White |
| Water Solubility | Water: slightly soluble |
| Stability: | Hygroscopic |
Safety information for Zanamivir-13C,15N2
Computed Descriptors for Zanamivir-13C,15N2
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