Zamifenacinfumarate

CAS NO.：127308-98-9
Empirical Formula: C31H33NO7
Molecular Weight: 531.61
MDL number: MFCD09263617
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-04 14:24:59

What is Zamifenacinfumarate?

The Uses of Zamifenacinfumarate

Zamifenacin Fumarate is a selective antagonist of mAChR M3 (M3 muscarinic receptor).

What are the applications of Application

Zamifenacin fumarate is a selective antagonist of mAChR M3 (M3 muscarinic receptor)

Biological Activity

Selective M 3 muscarinic receptor antagonist (pK i values are 8.52, 7.93, 7.90 and 7.78 for M 3 , M 2 , M 1 and M 4 receptors respectively). Displays higher affinity at ileal M 3 receptors (pK i = 9.3) compared to oesophageal and tracheal M 3 receptors (pK i values are 8.8 and 8.2 respectively). In vivo, inhibits gastrointestinal motility in the absence of cardiovascular effects.

Properties of Zamifenacinfumarate

storage temp.	Inert atmosphere,2-8°C
solubility	Soluble to 100 mM in DMSO and to 25 mM in ethanol
form	Powder
color	White to off-white

Safety information for Zamifenacinfumarate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Zamifenacinfumarate

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