Z-NH-5(ethylene glycol)-acetic acid
- CAS NO.：1449390-66-2
- Empirical Formula: C20H31NO9
- Molecular Weight: 429.46
- MDL number: MFCD31656969
- Update Date: 2026-05-28 01:07:04
What is Z-NH-5(ethylene glycol)-acetic acid?
Biological Activity
Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Safety information for Z-NH-5(ethylene glycol)-acetic acid
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