(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

CAS NO.：1987887-92-2
Empirical Formula: C24H21N3O3
Molecular Weight: 399.44
Update Date: 2025-07-14 15:27:00

What is (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate?

The Uses of (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester is an impurity of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

Properties of (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Melting point:	273 - 276°C
Boiling point:	641.3±55.0 °C(Predicted)
Density	1.316±0.06 g/cm3(Predicted)
storage temp.	Refrigerator, under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	11.16±0.20(Predicted)
color	Yellow to Orange

Safety information for (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Computed Descriptors for (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

New Products

Ketorolac EP Impurity A/ Ketorolac USP Related Compound B/ 1-Hydroxy Ketorolac Impurity Ketorolac EP Impurity C/ 6-Benzoyl Ketorolac Isomer Tacrolimus 8- propyl analog/Tacrolimus Monohydrate - Impurity E N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol Ivermectin Impurity F Isosulfan blue Keto N-Oxide Impurity L-phenylalanine methyl ester hydrochloride tri sodium thio phosphate L-phenylalanine, N-(pyrazinyl carbonyl) methyl ester 2-(3-amino propyl amino) ethyl bromide di hydrobromide N-[(1S)-1-benzyl-2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}amino)-2-oxoethyl]-2-pyrazinecarboxamide N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide CSA (DL-10-Camphorsulfonic Acid) (1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-5-yl)boronic acid (14bRS)-2-methyl-1,3,4,14b-tetrahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-10(2H)-one 7-(hydroxymethyl)-3,4-dihydroquinazolin-2(1H)-one 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioate (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 4-Methyl Benzene Propan Tert-Butyl 2-Diazoacetat 1,2,3,4-Tetrahydro-2-Oxo-4-Quinolinecarbonitrile Benzyl Carbonazidate 6-Bromo-7-Fluoro-3-Methyl-2(1h)-Quinoxalinone

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