YM 15430-1
- CAS NO.：153192-22-4
- Empirical Formula: C29H35N3O8
- Molecular Weight: 553.6
- MDL number: MFCD00892255
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is YM 15430-1?
Description
YM-430, also known as YM-15430; YM-154301; is a dual of β1 adrenergic receptor antagonist and calcium channel antagonist. YM430 could be both an antianginal and antihypertensive agent, because of its dual activities. YM430 (10(-8)-10(-6) M) inhibited 3,4-diaminopyridine-induced rhythmic contractions with an IC50 value of 59.2 nM. In anesthetized rats, YM430 (10-100 mg/kg PO) inhibited arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg PO. YM430 may be of value in the treatment of various types of angina pectoris such as variant and stable angina.
Properties of YM 15430-1
| Boiling point: | 729.3±60.0 °C(Predicted) |
| Density | 1.240±0.06 g/cm3(Predicted) |
| pka | 13.98±0.20(Predicted) |
Safety information for YM 15430-1
Computed Descriptors for YM 15430-1
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