YAP-TEAD-IN-1 TFA

CAS NO.：1659305-79-9
Empirical Formula: C95H145ClF3N23O23S2
Molecular Weight: 2133.91
MDL number: MFCD32693974
Update Date: 2025-08-21 22:16:43

What is YAP-TEAD-IN-1 TFA?

Biological Activity

YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer polypeptide with higher binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd=40 nM).

in vitro

YAP-TEAD-IN-1 (peptide 17)(2 μM) is against endogenous YAP binding to GST-TEAD(1209-426) in a GST pull-down assay, the K _{d < /sub> of His-YAP(1209-426) is determined to be 40 nM.}

Properties of YAP-TEAD-IN-1 TFA

storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	Soluble in DMSO
form	Solid
color	White to off-white

Safety information for YAP-TEAD-IN-1 TFA

Computed Descriptors for YAP-TEAD-IN-1 TFA

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