YAP-TEAD-IN-1 TFA
- CAS NO.：1659305-79-9
- Empirical Formula: C95H145ClF3N23O23S2
- Molecular Weight: 2133.91
- MDL number: MFCD32693974
- Update Date: 2026-07-16 07:06:08
What is YAP-TEAD-IN-1 TFA?
Biological Activity
YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer polypeptide with higher binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd=40 nM).
in vitro
YAP-TEAD-IN-1 (peptide 17)(2 μM) is against endogenous YAP binding to GST-TEAD(1209-426) in a GST pull-down assay, the K d < /sub> of His-YAP(1209-426) is determined to be 40 nM.
Properties of YAP-TEAD-IN-1 TFA
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| color | White to off-white |
Safety information for YAP-TEAD-IN-1 TFA
Computed Descriptors for YAP-TEAD-IN-1 TFA
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