XRK3F2
- CAS NO.：2375193-43-2
- Empirical Formula: C23H24ClF2NO3
- Molecular Weight: 435.9
- MDL number: MFCD31812777
- Update Date: 2026-07-16 07:06:08
What is XRK3F2?
Biological Activity
XRK3F2 is a p62-ZZ inhibitor that blunts multiple myeloma (MM)-induced Runx2 inhibition in vitro and induces new bone formation and remodeling in the presence of tumors in vivo.
in vivo
In vivo, XRK3F2 induces new bone formation and remodeling in tumors. The half-life of it in mice was 10.3 hours. In bone with multiple myeloma, it induced significant local new bone formation, but not in mice not directly inoculated with multiple myeloma cells.
Properties of XRK3F2
| storage temp. | Store at -20°C |
| solubility | DMSO : 150 mg/mL (344.12 mM);Water : 0.91 mg/mL (2.09 mM) |
| form | Solid |
| color | White to off-white |
Safety information for XRK3F2
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H320:Serious eye damage/eye irritation H372:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P314:Get medical advice/attention if you feel unwell. P403:Store in a well-ventilated place. |
Computed Descriptors for XRK3F2
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