WP-1034
- CAS NO.：857064-42-7
- Empirical Formula: C18H15N3O3
- Molecular Weight: 321.33
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-16 19:33:17
What is WP-1034?
Description
WP-1034 is a novel Jak-Stat inhibitor, which is active against AML blasts. WP-1034 effectively inhibited proliferation of OCIM2 cells and fresh AML samples. WP-1034 caused cell cycle arrest of OCIM2 cells in sub-Go phase. WP-1034 induced apoptosis of OCIM2 cells and that induction of apoptosis involved cleavage of caspase 3 and the DNA repair enzyme poly (adenosine diphosphate [ADP]-ribose) polymerase (PARP).
Properties of WP-1034
| Boiling point: | 553.4±50.0 °C(Predicted) |
| Density | 1.273±0.06 g/cm3(Predicted) |
| pka | 11.30±0.46(Predicted) |
Safety information for WP-1034
Computed Descriptors for WP-1034
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