WIKI4
Synonym(s):2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1Hbenz[de]isoquinoline-1,3(2H)-dione
- CAS NO.：838818-26-1
- Empirical Formula: C29H23N5O3S
- Molecular Weight: 521.59
- MDL number: MFCD05885187
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-17 13:05:51
What is WIKI4?
Description
Tankyrases (TNKS) cleave NAD+ to produce nicotinamide and ADP-
The Uses of WIKI4
WIKI4 is a novel Tankyrase inhibitor. It leads to inhibition of Wnt/?-catenin signaling.
What are the applications of Application
WIKI4 is a potent inhibitor of Wnt/β-catenin signaling
Storage
-20°C
Properties of WIKI4
| Boiling point: | 783.1±70.0 °C(Predicted) |
| Density | 1.37±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble10mg/mL, clear (warmed) |
| pka | 1.70±0.10(Predicted) |
| form | powder |
| color | white to beige |
Safety information for WIKI4
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for WIKI4
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