WAY-255348
- CAS NO.：872141-23-6
- Empirical Formula: C16H14FN3O
- Molecular Weight: 283.3
- MDL number: MFCD18782604
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-16 19:33:17
What is WAY-255348?
Description
WAY-255348 is a potent nonsteroidal progesterone receptor (PR) antagonist. WAY-255348 inhibits the activity of progesterone. WAY-255348 achieves antagonist activity by binding to and subsequently preventing progesterone-induced nuclear accumulation, phosphorylation and promoter interactions of the PR. WAY-255348 bound PR conformation was similar to that of a progesterone agonist-bound PR and distinct from steroidal antagonist-bound PR conformations. WAY-255348 inhibits PR action through a novel molecular mechanism that is distinct from previously studied PR modulators and may be a useful tool to further understanding of PR signaling pathways.
Properties of WAY-255348
| Boiling point: | 467.1±45.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| pka | 12.77±0.40(Predicted) |
Safety information for WAY-255348
Computed Descriptors for WAY-255348
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