WAY-255348

CAS NO.：872141-23-6
Empirical Formula: C16H14FN3O
Molecular Weight: 283.3
MDL number: MFCD18782604
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-16 19:33:17

What is WAY-255348?

Description

WAY-255348 is a potent nonsteroidal progesterone receptor (PR) antagonist. WAY-255348 inhibits the activity of progesterone. WAY-255348 achieves antagonist activity by binding to and subsequently preventing progesterone-induced nuclear accumulation, phosphorylation and promoter interactions of the PR. WAY-255348 bound PR conformation was similar to that of a progesterone agonist-bound PR and distinct from steroidal antagonist-bound PR conformations. WAY-255348 inhibits PR action through a novel molecular mechanism that is distinct from previously studied PR modulators and may be a useful tool to further understanding of PR signaling pathways.

Properties of WAY-255348

Boiling point:	467.1±45.0 °C(Predicted)
Density	1.28±0.1 g/cm3(Predicted)
pka	12.77±0.40(Predicted)

Safety information for WAY-255348

Computed Descriptors for WAY-255348

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