Wang-Yu non-directed C-H functionalization ligand

CAS NO.：38609-76-6
Empirical Formula: C7H3F6NO
Molecular Weight: 231.1
MDL number: MFCD28802532
Update Date: 2026-05-28 00:36:19

What is Wang-Yu non-directed C-H functionalization ligand?

The Uses of Wang-Yu non-directed C-H functionalization ligand

This 2-pyridone ligand developed in the laboratory of Jin-Quan Yu binds to palladium and accelerates non-directed C-H functionalization. Developed for C-H olefination and carboxylation with arene as the limiting reagent, the Wang-Yu ligand enables diversification of drugs, synthetic intermediates, and other bioactive small molecules.

Properties of Wang-Yu non-directed C-H functionalization ligand

Melting point:	145 °C
storage temp.	-20°C

Safety information for Wang-Yu non-directed C-H functionalization ligand

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Wang-Yu non-directed C-H functionalization ligand

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