VU-0486321
- CAS NO.：1816301-67-3
- Empirical Formula: C20H12ClFN2O4
- Molecular Weight: 398.77
- MDL number: MFCD32204661
- Update Date: 2026-04-21 10:31:43
What is VU-0486321?
Description
VU0486321 is a potent mGlu1 PAM with moderate rat PK (CLp = 13.3. mL/mikg,t1/2 = 54 min), good free fraction (human fu = 0.05, rat fu =0.03) and excellent CNS penetration (Kp = 1.02).
Properties of VU-0486321
| Density | 1.528±0.06 g/cm3(Predicted) |
| pka | 11.68±0.70(Predicted) |
Safety information for VU-0486321
Computed Descriptors for VU-0486321
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