Savolitinib
- CAS NO.：1313725-88-0
- Empirical Formula: C17H15N9
- Molecular Weight: 345.36
- MDL number: MFCD28359096
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-04 18:00:12
What is Savolitinib?
Description
Savolitinib selectively inhibits the MET receptor, blocking the PI3K/AKT/MAPK-signaling pathway as well as downregulating MYC.
The Uses of Savolitinib
Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.
Clinical Use
It is currently being evaluated in phase I clinical trials in combination with EGFR TKIs in NSCLC patients.
Properties of Savolitinib
| Melting point: | 205-207°C |
| Density | 1.55±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 5.67±0.50(Predicted) |
| form | Solid |
| color | Pale Beige |
| CAS DataBase Reference | 1313725-88-0 |
Safety information for Savolitinib
Computed Descriptors for Savolitinib
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