VlNDOLININE
- Empirical Formula: C21H26O2N2
- Molecular Weight: 0
What is VlNDOLININE?
Description
A hexacyclic alkaloid present in Vinca rosea L., the base forms colourless crystals and has [α]D - 18° (H20). It yields a dihydrochloride, m.p. 250-2°C; [α]20D - 26.8° (c 0.24, H20) and a picrate, m.p. 268-272°C. The alkaloid also form the N-acetyl derivative and on catalytic hydrogenation yields the dihydro compound. The structure has been established on the basis of the mass spectral fragmentation pattern and NMR measurements.
References
Gorman et aI., J. Arner. Pharrn. Assoc., 48, 256 (1959) Janot, LeMen, Kan-Fan., Bull. Soc. Chirn. Fr., 891 (1959) Structure: Djerassi et al., Proc. Nat. Acad. Sci, U.S., 48,113 (1962) Djerassietal., Helv. Chirn. Acta, 47,827 (1964)
Properties of VlNDOLININE
| Melting point: | 2l4-8°C |
Safety information for VlNDOLININE
Computed Descriptors for VlNDOLININE
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