VJ115
- CAS NO.：929256-79-1
- Empirical Formula: C23H24N2O
- Molecular Weight: 344.45
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-21 16:37:02
What is VJ115?
Description
VJ115 is a novel chemical entity that inhibits the enzyme ENOX1, a NADH oxidase. Genetic and small molecule inhibition of ENOX1 inhibits endothelial cell tubule formation and tumor-mediated neo-angiogenesis. Inhibition of ENOX1 radiosensitizes tumor vasculature, a consequence of enhanced apoptosis. VJ115 inhibition of ENOX1 can impact expression of proteins involved in cytoskeletal reorganization and support a hypothesis in which ENOX1 activity links elevated cellular NADH concentrations with cytoskeletal reorganization and angiogenesis.
Properties of VJ115
| Boiling point: | 593.0±50.0 °C(Predicted) |
| Density | 1.23±0.1 g/cm3(Predicted) |
| pka | 16.13±0.20(Predicted) |
Safety information for VJ115
Computed Descriptors for VJ115
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