VER-49009
- CAS NO.：558640-51-0
- Empirical Formula: C19H18ClN3O4
- Molecular Weight: 387.82
- MDL number: MFCD18382094
- EINECS: 604-604-1
- Update Date: 2026-04-22 18:57:36
What is VER-49009?
The Uses of VER-49009
VER 49009 is a heat shock protein 90 (HSP90) inhibitor. VER 49009 causes induction of HSP72 and HSP27 alongside depletion of client proteins, including C-RAF, B-RAF, and survivin, and the protein arginine methyltransferase PRMT5.
Definition
ChEBI: 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)pyrazole-3-carboxamide is an aromatic amide obtained by formal condensation of the carboxy group of 5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)pyrazole-3-carboxylic acid with the amino group of ethylamine. It has a role as a Hsp90 inhibitor. It is a member of pyrazoles, a member of resorcinols, a member of monochlorobenzenes, a monomethoxybenzene and an aromatic amide.
Properties of VER-49009
| Boiling point: | 620.2±55.0 °C(Predicted) |
| Density | 1.379±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : 100 mg/mL (257.85 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | Powder |
| pka | 7.86±0.25(Predicted) |
| color | White to off-white |
Safety information for VER-49009
Computed Descriptors for VER-49009
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloropyridazine 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane m-Tolualdehyde p-Anisaldehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid 6-Methyl-2-pyridinemethanol 2-Pyridinecarboxaldehdye tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 1-Indanone 2-Chloromethyl-6-methyl-pyridine 4-Morpholinoaniline Abiraterone Ethyl Ether 1-nitro-3,5-dimethyl adamantine (NMEM) Vardenafil Bis-sulphonamide(Dimer) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
![5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine](https://img.chemicalbook.in/CAS/GIF/1134156-31-2.gif)
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