valnoctamide
Synonym(s):2-ethyl-3-methyl-pentanamide;Axiquel;Nirvanil
- CAS NO.：4171-13-5
- Empirical Formula: C8H17NO
- Molecular Weight: 143.23
- MDL number: MFCD00868184
- EINECS: 224-033-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:55:42
What is valnoctamide?
Description
Valnoctamide is an isomer of the valproic acid amide, valpromide. It has been marketed as an anxiolytic and sedative compound and suppresses neuropathic pain. Unlike valpromide, valnoctamide is not metabolized to its acid form, valnoctic acid, in vivo and has no teratogenicity. It abolishes the activity of myo-inositol-1-phosphate synthase in human brain crude homogenates (Ki = 0.18 mM). Valnoctamide suppresses electrographic seizures in animal models of status epilepticus, suggesting potential applications in managing epilepsy.
Chemical properties
Crystalline Solid
The Uses of valnoctamide
Isomer of Valpromide. Anxiolytic
The Uses of valnoctamide
Isomer of Valpromide. Anxiolytic.
What are the applications of Application
Valnoctamide is an anxiolytic isomer of valpromide
Definition
ChEBI: Valnoctamide is a fatty amide.
brand name
Axiquel (Ortho-McNeil).
Properties of valnoctamide
| Melting point: | 113.5-1140C |
| Boiling point: | 261.35°C (rough estimate) |
| Density | 0.9636 (rough estimate) |
| refractive index | 1.4614 (estimate) |
| storage temp. | Refrigerator |
| solubility | DMSO: soluble20mg/mL, clear |
| form | powder |
| pka | 16.81±0.50(Predicted) |
| color | white to off-white |
| Water Solubility | 8.70g/L(temperature not stated) |
Safety information for valnoctamide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for valnoctamide
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