USP7-IN-1
- CAS NO.：1381291-36-6
- Empirical Formula: C23H24ClN3O3
- Molecular Weight: 425.91
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is USP7-IN-1?
Description
USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer. IC50: 77 μM (USP7)[1]
USP7-IN-1 (Example 2) is a selective and reversible inhibitor of USP7, with an IC50 of 77 μM, and shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3. USP7-IN-1 inhibits the proliferation of HCT116 cells, with a GI50 of 67 μM[1].
References
[1]. SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7. WO 2013030218 A1
Properties of USP7-IN-1
| Boiling point: | 666.2±65.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: ≥ 40 mg/mL (93.92 mM) |
| form | Solid |
| pka | 13.52±0.20(Predicted) |
| color | White to off-white |
Safety information for USP7-IN-1
Computed Descriptors for USP7-IN-1
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