UCM05
- CAS NO.：1094451-90-7
- Empirical Formula: C24H16O10
- Molecular Weight: 464.38
- Update Date: 2026-07-27 17:00:41
What is UCM05?
The Uses of UCM05
UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 μM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of HER2, Akt, and ERK1/2, and growth of established xenografts in vivo. UCM05 also blocks the GTP-binding site of the cell division protein FtsZ from Bacillus, preventing bacterial division.[Cayman Chemical]
The Uses of UCM05
G 28UCM is a fatty acid synthase inhibitor with anticancer activity, novel inhibitor of fatty acid synthase with anticancer activity.
Storage
Store at -20°C
Properties of UCM05
| Boiling point: | 895.1±65.0 °C(Predicted) |
| Density | 1.652±0.06 g/cm3(Predicted) |
| solubility | DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:40): 0.02 mg/ml |
| form | A crystalline solid |
| pka | 7.50±0.25(Predicted) |
| color | Off-white to light brown |
Safety information for UCM05
Computed Descriptors for UCM05
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