UAMC-3203

CAS NO.：2271358-64-4
Empirical Formula: C25H37N5O2S
Molecular Weight: 471.66
MDL number: MFCD31813707
Update Date: 2026-07-14 16:49:18

What is UAMC-3203?

Biological Activity

UAMC-3203 is a ferroptosis inhibitor with IC50 of 10 nM in IMR-32 neuroblastoma cells.

in vitro

UAMC-3203 was incubated with human microsomes or rat microsomes, and the T _1/2 were 20.5 h and 16.5 h, respectively. When co-incubated with mouse microsomes, UAMC-3203 showed relatively poor stability, with a T _1/2 of 3.46 h.

in vivo

In mice, UAMC-3203 can significantly reduce the plasma concentration of lactate dehydrogenase. After administration, it is rapidly removed from the blood and enters various tissues. Significant levels of UAMC-3203 were detected in the tissues tested, such as liver, kidney and lung.

Properties of UAMC-3203

Boiling point:	668.3±65.0 °C(Predicted)
Density	1.214±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Ethanol: Soluble
form	A crystalline solid
pka	12.27±0.50(Predicted)
color	White to off-white

Safety information for UAMC-3203

Computed Descriptors for UAMC-3203

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