TYRPHOSTIN B44
- CAS NO.：133550-32-0
- Empirical Formula: C18H16N2O3
- Molecular Weight: 308.33
- MDL number: MFCD00209854
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:14
What is TYRPHOSTIN B44?
The Uses of TYRPHOSTIN B44
Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase.
Biological Activity
Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.4 μ M), more active than the (+) enantiomer ((S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). Selective over ErbB2.
Properties of TYRPHOSTIN B44
| Boiling point: | 603.0±55.0 °C(Predicted) |
| Density | 1.299±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO or ethanol: soluble |
| form | Yellow solid. |
| pka | 8.81±0.10(Predicted) |
Safety information for TYRPHOSTIN B44
Computed Descriptors for TYRPHOSTIN B44
New Products
DL-beta-(3-Bromophenyl)alanine 1-Aminocyclopentane carbonitrile (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate Amlodipine EP Impurity-C Budesonide Impurity-K/Budesonide 21-Acetate (Epimers) Gabapentine Impurity 72 Bicalutamide Impurity-B Betahistine EP Impurity C Carbamazepine EP Impurity G 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 3-Hydroxypropionitrile 4-Bromo Benzylcyanide valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro BenzylcyanideRelated products of tetrahydrofuran
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