TYRPHOSTIN B44
- CAS NO.：133550-32-0
- Empirical Formula: C18H16N2O3
- Molecular Weight: 308.33
- MDL number: MFCD00209854
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-20 15:44:38
What is TYRPHOSTIN B44?
The Uses of TYRPHOSTIN B44
Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase.
Biological Activity
Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.4 μ M), more active than the (+) enantiomer ((S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). Selective over ErbB2.
Properties of TYRPHOSTIN B44
| Boiling point: | 603.0±55.0 °C(Predicted) |
| Density | 1.299±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO or ethanol: soluble |
| form | Yellow solid. |
| pka | 8.81±0.10(Predicted) |
Safety information for TYRPHOSTIN B44
Computed Descriptors for TYRPHOSTIN B44
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 2-Bromo-5-hydroxybenzoic acid. 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 4-Fluorophenylglycine 1-N-Boc-3-(aminoethyl)azetidine Dimedone 1-Boc-3-(cyanomethyl)azetidine N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile 5-Amino-2-Hydroxypyridine 2-Amino-5-Iodopyridine 2-BROMOACETYL BROMIDE-D2 METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR BENZENE-D6 TOLUENE-D3 6-Chloro-pyrimidine-2,4-diamine 3-Oxide 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
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