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tubulosine

tubulosine Structural

What is tubulosine?

Description

This alkaloid is a constituent of the bark of Pogonopus tubulosus (DC.) Schumann and is laevorotatory having [α]24D - 65.9° (c 2.0, pyridine). The ultraviolet spectrum in ethanol has an absorption maximum at 281Mu with a shoulder at 225 Mu. Two methoxyl groups, a phenolic hydroxyl group and two imino groups are present, the base yielding a crystalline monoacetyl derivative, m.p. l84-6°C and the diacetyl compound, m.p. l49-l5l°C.

Definition

ChEBI: A member of the class of beta-carbolines that is tubulosan bearing methoxy groups at positions 10 and 11 and a hydroxy group at the 8' position.

References

Brauchli et al., 1. Amer. Chem. Soc., 86, 1895 (1964)

Properties of tubulosine

Melting point: 282-283 °C
Boiling point: 667.8±55.0 °C(Predicted)
Density  1.27±0.1 g/cm3(Predicted)
pka 9.78±0.40(Predicted)

Safety information for tubulosine

Computed Descriptors for tubulosine

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