TTT-3002
- CAS NO.：871037-95-5
- Empirical Formula: C27H23N5O3
- Molecular Weight: 465.50322
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:59:17
What is TTT-3002?
Description
TTT-3002 is a tyrosine kinase inhibitor (TKI) that is one of the most potent FLT3 inhibitors discovered to date. Studies using human FLT3/ITD mutant leukemia cell lines revealed the half maximal inhibitory concentration (IC50) for inhibiting FLT3 autophosphorylation is from 100 to 250 pM. The proliferation IC50 for TTT-3002 in these same cells was from 490 to 920 pM. TTT-3002 also showed potent activity when tested against the most frequently occurring FLT3-activating point mutation, FLT3/D835Y, against which many current TKIs are ineffective.
Properties of TTT-3002
| Boiling point: | 770.4±60.0 °C(Predicted) |
| Density | 1.68±0.1 g/cm3(Predicted) |
| pka | 14.18±0.60(Predicted) |
Safety information for TTT-3002
Computed Descriptors for TTT-3002
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