TRIS(DIETHYLAMINO)PHOSPHINE
Synonym(s):Hexaethylphosphorous triamide;Tris(N,N-diethylamino)phosphine;Hexaethyltriamidophosphite;Hexaethyltriaminophosphine;Phosphorous acid tris(diethylamide)
- CAS NO.:2283-11-6
- Empirical Formula: C12H30N3P
- Molecular Weight: 247.36
- MDL number: MFCD00009041
- EINECS: 218-920-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:59:19
What is TRIS(DIETHYLAMINO)PHOSPHINE?
Chemical properties
clear colorless to yellow-orange liquid
The Uses of TRIS(DIETHYLAMINO)PHOSPHINE
Tris(diethylamino)phosphine [(Et2N)3P] can be used as a reagent to synthesize:
- 1,1′-Dialkylisoindigo derivatives by reacting with various 1-alkylisatins via deoxygenation reaction.
- 1-Aminomethylisatins by treating with isatin and primary and secondary amines.
It can also be used in the deoxygenation of some cyclic α-diketones using fullerene C60.
The Uses of TRIS(DIETHYLAMINO)PHOSPHINE
suzuki reaction
Properties of TRIS(DIETHYLAMINO)PHOSPHINE
| Melting point: | 230-232 °C |
| Boiling point: | 80-90 °C10 mm Hg(lit.) |
| Density | 0.903 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 58 °C |
| storage temp. | Store below +30°C. |
| form | Liquid |
| pka | 9.74±0.70(Predicted) |
| Specific Gravity | 0.903 |
| color | Clear colorless to yellow-orange |
| Water Solubility | Insoluble in water. |
| Sensitive | Air Sensitive |
| BRN | 636187 |
| CAS DataBase Reference | 2283-11-6(CAS DataBase Reference) |
| EPA Substance Registry System | Phosphorous triamide, hexaethyl- (2283-11-6) |
Safety information for TRIS(DIETHYLAMINO)PHOSPHINE
| Signal word | Warning |
| Pictogram(s) |
![]() Flame Flammables GHS02 ![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for TRIS(DIETHYLAMINO)PHOSPHINE
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
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