TRIS(2,2,2-TRIFLUOROETHYL) BORATE
Synonym(s):Sheppard Amidation Reagent;Sheppard Reagent;Tris(2,2,2-trifluoroethoxy)boron;Tris(2,2,2-trifluoroethyl)borate
- CAS NO.：659-18-7
- Empirical Formula: C6H6BF9O3
- Molecular Weight: 307.91
- MDL number: MFCD00093768
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-09 15:12:03
What is TRIS(2,2,2-TRIFLUOROETHYL) BORATE?
The Uses of TRIS(2,2,2-TRIFLUOROETHYL) BORATE
TRIS(2,2,2-TRIFLUOROETHYL) BORATE is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
The Uses of TRIS(2,2,2-TRIFLUOROETHYL) BORATE
Reagent can promote the direct formation of amides from carboxylic acids and amines under thermal and microwave conditions.
Properties of TRIS(2,2,2-TRIFLUOROETHYL) BORATE
| Boiling point: | 125°C(lit.) |
| Density | 1.430 g/mL at 25 °C |
| refractive index | n/D1.298(lit.) |
| Flash point: | 43℃ |
| storage temp. | Store at -20°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | clear liquid |
| color | Colorless to Almost colorless |
| EPA Substance Registry System | Tris(2,2,2-trifluoroethyl) borate (659-18-7) |
Safety information for TRIS(2,2,2-TRIFLUOROETHYL) BORATE
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02 |
| GHS Hazard Statements |
H226:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. |
Computed Descriptors for TRIS(2,2,2-TRIFLUOROETHYL) BORATE
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