(Trimethylsilyl)methylamine

Synonym(s):(Aminomethyl)trimethylsilane

CAS NO.：18166-02-4
Empirical Formula: C4H13NSi
Molecular Weight: 103.24
MDL number: MFCD00042931
EINECS: 242-049-2
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-27 23:13:47

What is (Trimethylsilyl)methylamine?

Purification Methods

A possible contaminant is hexamethyldisiloxane. It should have two 1H NMR signals in CDCl3; if not, dissolve it in *C6H6, shake it with 15% aqueous KOH, separate, dry (Na2SO4), filter, evaporate and distil it using a still of ca 10 theoretical plates. The water azeotrope has b 83o/735mm; hence it is important to dry the extract well. The hydrochloride has m 198-199o (from MeOH or Me2CO). [Noll et al. J Am Chem Soc 73 3867 1951, Beilstein 4 IV 3878.]

Properties of (Trimethylsilyl)methylamine

Melting point:	<0°C
Boiling point:	92-94 °C(lit.)
Density	0.771 g/mL at 20 °C(lit.)
refractive index	n20/D 1.416
Flash point:	9°C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	10.89±0.10(Predicted)
Specific Gravity	0.7697
Hydrolytic Sensitivity	4: no reaction with water under neutral conditions
BRN	1731488
CAS DataBase Reference	18166-02-4(CAS DataBase Reference)
NIST Chemistry Reference	Trimethylsilylmethylamine(18166-02-4)

Safety information for (Trimethylsilyl)methylamine

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05
GHS Hazard Statements	H225:Flammable liquids H314:Skin corrosion/irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.