TRIMETHYLSILYL TRIFLUOROACETATE
Synonym(s):Trifluoroacetic acid trimethylsilyl ester
- CAS NO.：400-53-3
- Empirical Formula: C5H9F3O2Si
- Molecular Weight: 186.2
- MDL number: MFCD00000413
- EINECS: 206-923-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-04 16:00:12
What is TRIMETHYLSILYL TRIFLUOROACETATE?
Chemical properties
clear colorless to light yellow liquid
The Uses of TRIMETHYLSILYL TRIFLUOROACETATE
Trimethysilyl Trifluoroacetate is a useful research chemical used as a promotor for stereoselective addition of silyl azides to meso epoxides.
Properties of TRIMETHYLSILYL TRIFLUOROACETATE
| Boiling point: | 88-90 °C(lit.) |
| Density | 1.078 g/mL at 25 °C(lit.) |
| vapor density | >1 (vs air) |
| refractive index | n |
| Flash point: | °C |
| storage temp. | Flammables area |
| form | Powder |
| color | White |
| Specific Gravity | 1.078 |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| BRN | 1773314 |
| CAS DataBase Reference | 400-53-3(CAS DataBase Reference) |
| EPA Substance Registry System | Acetic acid, trifluoro-, trimethylsilyl ester (400-53-3) |
Safety information for TRIMETHYLSILYL TRIFLUOROACETATE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H225:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for TRIMETHYLSILYL TRIFLUOROACETATE
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