TRIMETHYLSILYL BROMOACETATE
- CAS NO.：18291-80-0
- Empirical Formula: C5H11BrO2Si
- Molecular Weight: 211.13
- MDL number: MFCD00000187
- EINECS: 242-165-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:03
What is TRIMETHYLSILYL BROMOACETATE?
Chemical properties
Clear slightly yellow liquid
The Uses of TRIMETHYLSILYL BROMOACETATE
Trimethylsilyl bromoacetate has been used:
- in the preparation of new imidazolium salts functionalized with the trimethylsilyl ester group
- as alkylating agent in the synthesis of succinate fragment of pantocin B (antibiotic natural product)
- in the synthesis of taxol derivatives tethered at C2′ and C-7 to glutamate and folate
Properties of TRIMETHYLSILYL BROMOACETATE
| Boiling point: | 57-58 °C/9 mmHg (lit.) |
| Density | 1.284 g/mL at 25 °C (lit.) |
| vapor density | >1 (vs air) |
| refractive index | n |
| Flash point: | 83 °F |
| storage temp. | Flammables area |
| form | clear liquid |
| color | Colorless to Light yellow |
| Specific Gravity | 1.299 |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| Sensitive | Moisture Sensitive |
| BRN | 1927560 |
| CAS DataBase Reference | 18291-80-0(CAS DataBase Reference) |
Safety information for TRIMETHYLSILYL BROMOACETATE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H226:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for TRIMETHYLSILYL BROMOACETATE
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