TRIMETHYLPHOSPHINE OXIDE
- CAS NO.：676-96-0
- Empirical Formula: C3H9OP
- Molecular Weight: 92.08
- MDL number: MFCD00013910
- EINECS: 211-633-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-08 17:45:00
What is TRIMETHYLPHOSPHINE OXIDE?
The Uses of TRIMETHYLPHOSPHINE OXIDE
Trimethylphosphine oxide is a common side product in organic synthesis, including the Wittig, Staudinger, Mitsunobu reactions and also in the manufacture of triphenylphosphine. It is a popular reagent to induce the crystallization of various chemical compounds. It acts as an excellent ligand for hard metal centers. It can react with 9-methyl-9-azonianthracene methyl sulfate to get (10-methyl-9,10-dihydro-acridin-9-yl)-phosphonic acid dimethyl ester using sodium iodide and acetonitrile as solvent.
Properties of TRIMETHYLPHOSPHINE OXIDE
| Melting point: | 140-141°C |
| Boiling point: | 194℃ |
| Density | 0.900 |
| Flash point: | 71℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Soluble in polar organic solvents. |
| form | Crystalline |
Safety information for TRIMETHYLPHOSPHINE OXIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for TRIMETHYLPHOSPHINE OXIDE
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