Trimethylamine N-oxide dihydrate

Synonym(s):TMANO

CAS NO.：62637-93-8
Empirical Formula: C3H13NO3
Molecular Weight: 111.14
MDL number: MFCD00149077
EINECS: 678-501-4
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-27 17:00:41

Trimethylamine N-oxide dihydrate Structural

What is Trimethylamine N-oxide dihydrate?

Chemical properties

white crystalline powder

The Uses of Trimethylamine N-oxide dihydrate

Trimethylamine N-Oxide Dihydrate is as an oxygen transfer agent used to promote heterometallic cluster catalyzing coordinative hydrogenation. Trimethylamine N-Oxide Dihydrate is also used as a catalyst in the preparation of thermally stable TiO2 nanorod incorporated polymers and semiconductor/metal nanocomposites.

The Uses of Trimethylamine N-oxide dihydrate

Oxidizing reagent in organic synthesis.

The Uses of Trimethylamine N-oxide dihydrate

Trimethylamine N-oxide dihydrate is used as an oxidizing agent in organic synthesis. It is also used to make quaternary ammonium compounds and a warning agent for flammable gas. Further, it acts as a flavoring agent or adjuvant. It serves as an oxidant for the catalytic osmium tetraoxide cis-hydroxylation of hindered olefins. In addition to this, it is used as a reactant for C-H bond cleavage and decarbonylating agent for solvent-free reactions.

General Description

Trimethylamine N-oxide (TMAO) is an amphiphilic osmolyte that can counteract the denaturing effects of urea, pressure, and ice and stabilize the proteins.

Properties of Trimethylamine N-oxide dihydrate

Melting point:	95-99 °C(lit.)
Flash point:	95 °C
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Sparingly)
form	Fine Crystalline Powder
color	White to off-white
Water Solubility	Soluble in water, ethanol, dimethyl sulfoxide and methanol. Sparingly soluble in hot chloroform. Insoluble in diethyl ether, benzene and hydrocarbon solvents.
Merck	14,9711
BRN	3612927
CAS DataBase Reference	62637-93-8(CAS DataBase Reference)

Safety information for Trimethylamine N-oxide dihydrate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.