Trimethylamine N-oxide dihydrate
Synonym(s):TMANO
- CAS NO.：62637-93-8
- Empirical Formula: C3H13NO3
- Molecular Weight: 111.14
- MDL number: MFCD00149077
- EINECS: 678-501-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is Trimethylamine N-oxide dihydrate?
Chemical properties
white crystalline powder
The Uses of Trimethylamine N-oxide dihydrate
Trimethylamine N-Oxide Dihydrate is as an oxygen transfer agent used to promote heterometallic cluster catalyzing coordinative hydrogenation. Trimethylamine N-Oxide Dihydrate is also used as a catalyst in the preparation of thermally stable TiO2 nanorod incorporated polymers and semiconductor/metal nanocomposites.
The Uses of Trimethylamine N-oxide dihydrate
Oxidizing reagent in organic synthesis.
The Uses of Trimethylamine N-oxide dihydrate
Trimethylamine N-oxide dihydrate is used as an oxidizing agent in organic synthesis. It is also used to make quaternary ammonium compounds and a warning agent for flammable gas. Further, it acts as a flavoring agent or adjuvant. It serves as an oxidant for the catalytic osmium tetraoxide cis-hydroxylation of hindered olefins. In addition to this, it is used as a reactant for C-H bond cleavage and decarbonylating agent for solvent-free reactions.
General Description
Trimethylamine N-oxide (TMAO) is an amphiphilic osmolyte that can counteract the denaturing effects of urea, pressure, and ice and stabilize the proteins.
Properties of Trimethylamine N-oxide dihydrate
| Melting point: | 95-99 °C(lit.) |
| Flash point: | 95 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Sparingly) |
| form | Fine Crystalline Powder |
| color | White to off-white |
| Water Solubility | Soluble in water, ethanol, dimethyl sulfoxide and methanol. Sparingly soluble in hot chloroform. Insoluble in diethyl ether, benzene and hydrocarbon solvents. |
| Merck | 14,9711 |
| BRN | 3612927 |
| CAS DataBase Reference | 62637-93-8(CAS DataBase Reference) |
Safety information for Trimethylamine N-oxide dihydrate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Trimethylamine N-oxide dihydrate
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