Triisopropyl orthoformate
- CAS NO.：4447-60-3
- Empirical Formula: C10H22O3
- Molecular Weight: 190.28
- MDL number: MFCD00060628
- EINECS: 224-688-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:54
What is Triisopropyl orthoformate?
Chemical properties
clear colourless liquid
The Uses of Triisopropyl orthoformate
Triisopropyl Orthoformate (cas# 4447-60-3) is a compound useful in organic synthesis.
The Uses of Triisopropyl orthoformate
Triisopropyl orthoformate may be used for the preparation of 2-(diisopropoxymethyl)oxirane.
General Description
Triisopropyl orthoformate (TIPO) is formed during the reaction of dichlorofluoromethane with potassium isopropoxide in isopropyl alcohol. Separation of TIPO from n-hexane by dense carbon nanotube (CNT) membranes by pervaporation has been reported.
Properties of Triisopropyl orthoformate
| Boiling point: | 65-66 °C/18 mmHg (lit.) |
| Density | 0.854 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 108 °F |
| storage temp. | Flammables area |
| form | Liquid |
| color | Clear colorless |
| Sensitive | Moisture Sensitive |
| BRN | 1700668 |
| CAS DataBase Reference | 4447-60-3(CAS DataBase Reference) |
| EPA Substance Registry System | Propane, 2,2',2''-[methylidynetris(oxy)]tris- (4447-60-3) |
Safety information for Triisopropyl orthoformate
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Triisopropyl orthoformate
| InChIKey | FPIVAWNGRDHRSQ-UHFFFAOYSA-N |
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