Trimethyl orthoacetate
Synonym(s):1,1,1-Trimethoxyethane;1,1,1-Trimethoxyethane, Orthoacetic acid trimethyl ester;Trimethyl orthoacetate
- CAS NO.：1445-45-0
- Empirical Formula: C5H12O3
- Molecular Weight: 120.15
- MDL number: MFCD00008477
- EINECS: 215-892-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-11 21:28:41
What is Trimethyl orthoacetate?
Chemical properties
CLEAR COLOURLESS TO SLIGHTLY BROWN LIQUID
The Uses of Trimethyl orthoacetate
Trimethyl orthoacetate has been used in the preparation of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-amino-9-(3-alkoxycarbonyl-oxymethyl-4-alkoxycarbonyloxybut -1-yl)purines.
General Description
Kinetics and mechanism of gas-phase elimination of trimethyl orthoacetate has been examined over the temperature range of 310-369°C and pressure range of 50-130Torr.
Properties of Trimethyl orthoacetate
| Boiling point: | 107-109 °C(lit.) |
| Density | 0.944 g/mL at 25 °C(lit.) |
| vapor pressure | 20 hPa (20 °C) |
| refractive index | n |
| Flash point: | 62 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Liquid |
| color | Clear colorless to slightly brown |
| Specific Gravity | 0.960 (20/4℃) |
| Water Solubility | HYDROLYSIS |
| Sensitive | Moisture Sensitive |
| BRN | 1098338 |
| CAS DataBase Reference | 1445-45-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethane, 1,1,1-trimethoxy-(1445-45-0) |
| EPA Substance Registry System | Trimethyl orthoacetate (1445-45-0) |
Safety information for Trimethyl orthoacetate
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H317:Sensitisation, Skin H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Trimethyl orthoacetate
| InChIKey | HDPNBNXLBDFELL-UHFFFAOYSA-N |
Trimethyl orthoacetate manufacturer
JSK Chemicals
2Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 1445-45-0 Trimethyl orthoacetate, 98% 99%
Antares Chem Private Limited
Mumbai
product: Liquid Transparent Trimethyl Orthoacetate For Industrial, Packaging Type: Drum
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