Trigonelline hydrochloride
Synonym(s):1-Methylpyridinium-3-carboxylate hydrochloride;N-Methylnicotinic acid betaine hydrochloride;Trigonelline hydrochloride
- CAS NO.：6138-41-6
- Empirical Formula: C7H8ClNO2
- Molecular Weight: 173.6
- MDL number: MFCD00077250
- EINECS: 228-119-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is Trigonelline hydrochloride?
Description
Trigonelline hydrochloride (N-methylnicotinic acid betaine hydrochloride) is a betaine type pyrimidine alkaloid found in various seeds, including coffee beans. Trigonelline is synthesized from nicotinic acid in many plant species. It has been reported that trigonelline has diverse biological activities, such as hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities. (The product is for research purpose only.)
The Uses of Trigonelline hydrochloride
Trigonelline (chloride) is an alkaloid found in plants and coffee. Trigonelline is a product of niacin metabolism that is excreted in urine.
What are the applications of Application
Trigonelline hydrochloride is an analytical standard for proteomics research
References
Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease (a review)
J. Zhou, L. Chan, S. Zhou, Curr. Med. Chem. 2012, 19, 3523.
A Review on Biosynthesis, Analytical Techniques, and Pharmacological Activities of Trigonelline as a Plant Alkaloid
N. Mohamadi, F. Sharififar, M. Pournamdari, M. Ansari, J. Dietary Suppl. 2018, 15, 207.
Properties of Trigonelline hydrochloride
| Melting point: | ~260 °C (dec.) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Methanol (Slightly), Water |
| form | neat |
| form | Solid |
| color | White to Off-White |
| Merck | 14,9694 |
| BRN | 3734169 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 6138-41-6(CAS DataBase Reference) |
Safety information for Trigonelline hydrochloride
Computed Descriptors for Trigonelline hydrochloride
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