TRAUMATIC ACID

CAS NO.：6402-36-4
Empirical Formula: C12H20O4
Molecular Weight: 228.28
MDL number: MFCD00004443
EINECS: 229-019-4
SAFETY DATA SHEET (SDS)
Update Date: 2025-10-29 15:43:00

What is TRAUMATIC ACID?

Description

Traumatic acid, formally?trans-2-dodecenedioic acid, is a plant hormone that was isolated from damaged green beans by Caltech chemists James English, Jr., James Bonner, and A. J. Haagen-Smit in 1939. They describe traumatic acid and its acid–aldehyde cousin traumatin as “wound hormones” that is, substances produced by a plant to “heal” itself after it is damaged.
The same year, English et al.?synthesized traumatic acid?by converting undecylenic acid to the half-aldehyde of sebacic acid, which they then condensed with malonic acid in the presence of pyridine. CO2?was split off after the condensation, and the unsaturated diacid was isolated after hydrolysis of the ester group.
Traumatic acid may heal wounds in plants, but it may also be symbolic of American society’s wounds during this election season. May your trauma be kept to a minimum.

Chemical properties

white to beige crystalline powder

The Uses of TRAUMATIC ACID

Traumatic Acid, is the product of a biosynthetic pathway from a physiological role of alpha-ketol fatty acids in plant lipid hydroperoxide lyase metabolism. This compound is also used in would healing as it stimulates cell division to form a protective callus around the wound site.

What are the applications of Application

Traumatic Acid is a product of the hydroperoxide lyase pathway in plants

Definition

ChEBI: A monounsaturated straight-chain dicarboxylic acid with the double bond at C-2; a plant wound-healing hormone.

Purification Methods

Crystallise the acid from EtOH, acetone or glyme. The bis-4-phenylphenacyl ester has m 144-145o (from EtOH). [Beilstein 2 III 1978, 2 IV 2279.]

Properties of TRAUMATIC ACID

Melting point:	165-167 °C(lit.)
Boiling point:	290.1°C (rough estimate)
Density	1.0051 (rough estimate)
refractive index	1.4627 (estimate)
storage temp.	2-8°C
solubility	Chloroform (Very Slightly, Heated), DMSO (Slightly)
form	Solid
pka	4.78±0.10(Predicted)
color	White to Off-White
Merck	14,9576
CAS DataBase Reference	6402-36-4(CAS DataBase Reference)

Safety information for TRAUMATIC ACID

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection.