Tianeptine
- CAS NO.：72797-41-2
- Empirical Formula: C21H25ClN2O4S
- Molecular Weight: 436.95
- MDL number: MFCD00865376
- EINECS: 276-851-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 22:46:29
What is Tianeptine?
Chemical properties
White Solid
The Uses of Tianeptine
Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.
Definition
ChEBI: Tianeptine is a racemate comprising of equimolar amounts of (R)- and (S)-tianeptine. It is an atypical antidepressant used in Europe to treat patients who respond poorly to selective serotonin reuptake inhibitors (SSRIs). It has a role as a mu-opioid receptor agonist, a second generation antipsychotic and an anxiolytic drug. It contains a (R)-tianeptine and a (S)-tianeptine.
brand name
Stablon, Tatinol, and Coaxil among others
Mechanism of action
Current research suggests that tianeptine produces its antidepressant effects through the modulation of glutamate receptor activity (for example, AMPA receptors and NMDA receptors) and affect the release of brain-derived neurotrophic factor (BDNF), which impacts neural plasticity.
Properties of Tianeptine
| Melting point: | 129-131?C |
| Boiling point: | 609.2±65.0 °C(Predicted) |
| Density | 1.38±0.1 g/cm3(Predicted) |
| vapor pressure | 0.001Pa at 25℃ |
| storage temp. | Refrigerator, Under Inert Atmosphere |
| pka | 4.75±0.10(Predicted) |
| form | solid |
Safety information for Tianeptine
Computed Descriptors for Tianeptine
| InChIKey | JICJBGPOMZQUBB-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CCCCCCNC1C2=CC=C(Cl)C=C2S(=O)(=O)N(C)C2=CC=CC=C21 |
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