Tetrakis(hydroxymethyl)phosphonium sulfate

Synonym(s):Tetrakis(hydroxymethyl)phosphonium sulfate

CAS NO.：55566-30-8
Empirical Formula: C8H24O12P2S
Molecular Weight: 406.28
MDL number: MFCD00054243
EINECS: 259-709-0
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:27:08

Tetrakis(hydroxymethyl)phosphonium sulfate Structural

What is Tetrakis(hydroxymethyl)phosphonium sulfate ?

Description

Tetrakis(hydroxymethyl)phosphonium sulfate (THPS) is an organophosphorus compound. It is used as a precursor in the flame retardant manufacturing process, a biocide in water systems, and a tanning agent in the leather industry. THPS is a safe aqueous solution with antimicrobial properties that is significantly less toxic, effective at lower concentrations, and more biodegradable than other traditional biocides.

General Description

Clear colorless viscous liquid.

Air & Water Reactions

Water soluble.

Reactivity Profile

Tetrakis(hydroxymethyl)phosphonium sulfate is incompatible with oxidizing materials and alkalis.

Fire Hazard

Tetrakis(hydroxymethyl)phosphonium sulfate is probably combustible.

Flammability and Explosibility

Non flammable

Advantages

Advantage of the wet white tanned leathers, using THPS offers:
a light color and pastel shades
They can reach shrink temperatures of at least 70 grad C
High softness
Good lightness
Feeling of naturalness
Pleasant to the touch
Beauty that lasts for a long time
Can be burned without the risk of hexavalent chromium formation

Properties of Tetrakis(hydroxymethyl)phosphonium sulfate

Melting point:	-35°C
Boiling point:	111°C
Density	1.4 g/mL at 25 °C(lit.)
vapor pressure	0Pa at 20℃
Flash point:	96 °C
storage temp.	Sealed in dry,Room Temperature
form	liquid
color	Colorless to Almost colorless
Specific Gravity	1.42
Water Solubility	>=10 g/100 mL at 18 ºC
BRN	8521357
InChI	InChI=1S/C4H12O4P.H2O4S/c5-1-9(2-6,3-7)4-8;1-5(2,3)4/h5-8H,1-4H2;(H2,1,2,3,4)/q+1;/p-1
CAS DataBase Reference	55566-30-8(CAS DataBase Reference)
EPA Substance Registry System	Tetrakis(hydroxymethyl)phosphonium sulfate (55566-30-8)

Safety information for Tetrakis(hydroxymethyl)phosphonium sulfate

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H350:Carcinogenicity H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention.