Tetrahydropiperine
- CAS NO.：23434-88-0
- Empirical Formula: C17H23NO3
- Molecular Weight: 289.37
- MDL number: MFCD17167032
- EINECS: 000-000-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:56:38
What is Tetrahydropiperine?
Chemical properties
Light yellow crystalline powder, easily soluble in chloroform and ethyl acetate, soluble in hot ethanol and hot benzene, insoluble in water and petroleum ether, derived from the dry near-ripe or ripe fruit of Piper nigrum L.
Definition
ChEBI: Tetrahydropiperine is a member of benzodioxoles.
Biological Activity
Tetrahydropiperine is a cyclohexyl analog of piperine, the first natural arylvaleramide from Piper longum. Tetrahydropiperine (compound 14) inhibits the cytochrome P450 (CYP) isoform CYP1A1/aryl hydrocarbon hydroxylase (AHH; IC50=23 μM).
Properties of Tetrahydropiperine
| Boiling point: | 261 °C(Press: 14 Torr) |
| Density | 1.156±0.06 g/cm3(Predicted) |
| solubility | DMF: 10 mg/mL; DMSO: 10 mg/mL; DMSO:PBS (pH 7.2) (1:7): 0.1 mg/mL; Ethanol: 10 mg/mL |
| pka | -0.44±0.20(Predicted) |
| form | Solid |
| color | White to off-white |
Safety information for Tetrahydropiperine
Computed Descriptors for Tetrahydropiperine
Tetrahydropiperine manufacturer
GK Chemicals
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product: Tetrahydropiperin 23434-88-0 >98%
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