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HomeProduct name listTETRAHYDROPIPERINE

TETRAHYDROPIPERINE

  • CAS NO.:23434-88-0
  • Empirical Formula: C17H23NO3
  • Molecular Weight: 289.37
  • MDL number: MFCD17167032
  • EINECS: 000-000-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2026-06-25 15:33:52
TETRAHYDROPIPERINE Structural

What is TETRAHYDROPIPERINE?

Chemical properties

Light yellow crystalline powder, easily soluble in chloroform and ethyl acetate, soluble in hot ethanol and hot benzene, insoluble in water and petroleum ether, derived from the dry near-ripe or ripe fruit of Piper nigrum L.

Definition

ChEBI: Tetrahydropiperine is a member of benzodioxoles.

Biological Activity

Tetrahydropiperine is a cyclohexyl analog of piperine, the first natural arylvaleramide from Piper longum. Tetrahydropiperine (compound 14) inhibits the cytochrome P450 (CYP) isoform CYP1A1/aryl hydrocarbon hydroxylase (AHH; IC50=23 μM).

Properties of TETRAHYDROPIPERINE

Boiling point: 261 °C(Press: 14 Torr)
Density  1.156±0.06 g/cm3(Predicted)
solubility  DMF: 10 mg/mL; DMSO: 10 mg/mL; DMSO:PBS (pH 7.2) (1:7): 0.1 mg/mL; Ethanol: 10 mg/mL
pka -0.44±0.20(Predicted)
form  Solid
color  White to off-white

Safety information for TETRAHYDROPIPERINE

Computed Descriptors for TETRAHYDROPIPERINE

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