tetrahydroharmine
- CAS NO.：17019-01-1
- Empirical Formula: C13H16N2O
- Molecular Weight: 216.28
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-11-09 13:47:42
What is tetrahydroharmine?
Description
This carboline alkaloid is present in Banisteria caapi, a plant indigenous toSouth America. It is dextrorotatory with [o:]l>s + 32° (c 1.0, CHCI3). One methoxyl group, a methyl group and two imino groups are present in the molecule.
The Uses of tetrahydroharmine
Tetrahydroharmine is a β-Carboline derivative. β-Carboline alkaloids are inhibitors of human monoamine oxidase enzymes. β-carboline derivatives were also reported to have antiviral and fungicidal activity. Tetrahydroharmine is related to 3,4-Dihydroharmine (D449718).
References
Hochstein, Paradies., J. Arner. Chern. Soc., 79, 5735 (1957)
Bernauer., Helv. Chirn. Acta, 47, 1075 (1960)
Koblicova, Trojanek., Chern. Ind., 1342 (1966)
Properties of tetrahydroharmine
| Melting point: | 199 °C |
| Boiling point: | 399.2±37.0 °C(Predicted) |
| Density | 1.145±0.06 g/cm3(Predicted) |
| storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 18.03±0.40(Predicted) |
| color | White to Off-White |
| Stability: | Light Sensitive |
Safety information for tetrahydroharmine
Computed Descriptors for tetrahydroharmine
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