FUMITREMORGIN C
Synonym(s):Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem;NSC719655, FTC
- CAS NO.：118974-02-0
- Empirical Formula: C22H25N3O3
- Molecular Weight: 379.45
- MDL number: MFCD08702652
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-11-04 16:48:37
What is FUMITREMORGIN C?
The Uses of FUMITREMORGIN C
Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.
The Uses of FUMITREMORGIN C
Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.
What are the applications of Application
Fumitremorgin C is a strong and specific BRCP inhibitor
Definition
ChEBI: An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.
General Description
A cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug transport activity. Also acts as a potent and specific chemosenzitizing agent.
Biochem/physiol Actions
Cell permeable: yes
Storage
+4°C
Properties of FUMITREMORGIN C
| Melting point: | 259.5-260.5℃ |
| Boiling point: | 642.9±55.0 °C(Predicted) |
| Density | 1.34±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | acetonitrile: 5 mg/mL, soluble |
| form | solid |
| pka | 17.16±0.40(Predicted) |
| color | White to light brown |
Safety information for FUMITREMORGIN C
Computed Descriptors for FUMITREMORGIN C
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